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MIF demonstrates chemokine-like operate and was discovered to be a ligand of both CXCR2 and CXCR4. Binding of MIF to these receptors enhances monocyte recruitment and leukocyte chemotaxis (Figure 1). In human chondrosarcoma cells, this recruitment is mediated by Gαi proteins and PI3K in T mobile adhesion via upregulation with the transcription fro
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